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Celiac Antibody Profile by US BioTek. Celiac disease is a permanent intolerance to gluten found in wheat, rye and barley. Semi-quantitative Assay that includes: Anti-Tissue Transglutaminase IgA (tTg‐IgA) Anti-Gliadin IgA (AGA‐IgA) Anti-Gliadin IgG (AGA‐IgG)
Celiac Antibody Profile. Celiac disease is a permanent intolerance to gluten found in wheat, rye and barley. Semi-quantitative Assay that includes: Anti-Tissue Transglutaminase IgA (tTg‐IgA) Anti-Gliadin IgA (AGA‐IgA) Anti-Gliadin IgG (AGA‐IgG)
The immune reaction to the gluten protein in the gut sets off an inflammatory state that may cause diarrhea, abdominal cramping, distension, flatulence, weight loss, fatigue and malaise. Untreated CD may lead to vitamin and mineral deficiencies, osteoporosis, arthralgias, dermatitis herpetiformis, depression, irritability and impaired scholastic performance in children.
In the U.S. the prevalence of celiac disease is approximately 1%.
Celiac Disease symptoms include:
Gastrointestinal Symptoms—Pain, Diarrhea/
Constipation, Vomiting, Distension; First
Degree Relatives of Patients with Celiac
Disease; Iron Deficiency Anemia; Osteoporosis
or Osteomalacia; Type I Diabetes Mellitus; Liver
Disease; Genetic Disorders—Down Syndrome,
Turner's Syndrome; Reproductive Disorders—
Delayed Menarche, Unexplained Infertility;
Other Existing Disease or Autoimmune Disorder—
Addison's Disease, IgA Nephropathy,
Autoimmune Thyroid Disease,
Idiopathic Epilepsy, Sjögren's syndrome.
ELISA Celiac Antibody Panel is a semi-quantitative analysis of serum Anti-Tissue Transglutaminase IgA (tTg IgA), in addition to IgG and IgA antibodies specific for gliadin.
Anti-Tissue Transglutaminase IgA (tTg IgA) is a highly sensitive (about 98%) and specific (>95%) marker for untreated celiac disease in an IgA competent individual.
Anti-Gliadin IgA and Anti-Gliadin IgG are useful markers to monitor compliance to a gluten-free diet.
Serum (2 ml) or Finger Stick (8 saturated blood collection strips)
Whole Blood (Blood Spot Collection Card) Kit Contents:
2 Alcohol Swabs. 2 Lancets. * Blood Spot Collection Card. 2 Bandages. 1 Non-Latex Glove. 1 Prepaid Return Envelope. 1 Test Requisition Form.
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